As climate change and environmental degradation reshape the risk landscape, Sand Fly-Borne Diseases (SFBDs), including Leishmaniasis and viruses such as Toscana (TOSV), are no longer restricted to southern latitudes. Recent evidence from the CLIMOS project indicates that climate suitability for sand fly vector species are is expected to increase in endemic regions including southwest Iberia, the south and southwest coasts of France, coastal regions in Italy and in the Balkans, and west and central Turkey, with emerging risks in previously unaffected regions including Austria, Germany and the Netherlands. This brief translates field-based evidence from 13 countries into actionable policy goals. We believe these results will be instrumental in shaping future guidance for disease prevention.